WebJun 25, 2012 · Bevacizumab (Avastin ®) has been used by ophthalmologists in many countries as an off-label drug for the treatment of wet age-related macular degeneration (AMD).Due to its short half-life necessitating frequent intravitreal injection, a method for sustained delivery is in need. We demonstrated that bevacizumab could be released in a … Web326 𝑌𝑡 = ⍺𝑖 + 𝛽 𝑋´𝑡 + 𝐷´1𝑡 𝐷´𝛾1 ∑𝑟𝑗=−𝑞 ∆𝑋´𝑡+𝑗 ⍴ + 𝑣1,𝑡 (16) 327 From the above equation, the differenced explanatory variables with lag and lead of 𝑞 and 𝑟 328 accordingly absorb all the long-run relationship between 𝑣1,𝑡 and 𝑣2,𝑡 while the least-square estimates 329 of θ …
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