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WebCurrently, five peptide modulators of acid-sensing ion channels (ASICs) attributed to structural class 1b of sea anemone toxins have been described. The APETx2 toxin is the first and most potent ASIC3 inhibitor, so its homologs from sea anemones are known as the APETx-like peptides. We have discovered that two APETx-like peptides from the sea … WebSodium channels consist of large alpha subunits that associate with proteins, such as beta subunits.An alpha subunit forms the core of the channel and is functional on its own. When the alpha subunit protein is expressed by a cell, it is able to form channels that conduct Na + in a voltage-gated way, even if beta subunits or other known modulating proteins are not … drag switch
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