Fischer rat thyroid
WebFeb 17, 2024 · The Fischer rat thyroid follicular cell line (FRTL-5) endogenously expresses the sodium-iodide symporter (NIS) and has been used to identify environmental chemicals that perturb thyroid hormone homeostasis by disruption of NIS-mediated iodide uptake. WebFischer rat thyroid cells (FRTL) were treated with Novasoy (a soy alcohol extract containing 30% ISF) or major ISF aglycones or glycosides for 24 h. Iodide uptake was measured by a colorimetric assay. The protein level of Tg and NIS was measured by Western blotting.
Fischer rat thyroid
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Webment of the kinetics of iodide influx in Fisher rat thyroid cells expressing wild-type or G551D CFTR together with the green fluorescent protein-based halide indicator YFP-H148Q. Duplicate screenings revealed that 204 compounds did not significantly affect CFTR function. Compounds of the 7,8-benzoflavone class, which are WebMaintaining healthy cells is the key to experimental success and reproducible research results. To give you confidence in the health of your cells every step of the way, we’ve highlighted the technologies and products within cell biology that are critical to maintaining optimal cell health.
WebApr 22, 2024 · The Fischer rat thyroid follicular cell line, FRTL-5, endogenously expresses the sodium iodide symporter (NIS) and has been used to identify environmental chemicals that perturb thyroid hormone homeostasis by disruption of NIS-mediated uptake of iodide. Previously, a high-throughput radioactive iodide uptake (RAIU) screening assay using … WebThis study investigated the effects of thyroid disruption of malathion in Fischer rat thyroid follicular cell line, FRTL-5. Transcriptional and translational analyses on thyroglobulin demonstrated that both mRNA and protein expression levels were significantly inhibited by …
WebFischer Rat Thyroid (FRT) cells have been used extensively for studies of cystic fibrosis transmembrane conductance regulator (CFTR) protein for more than 20 years and have been a ”workhorse” for drug discovery in … WebWe would like to show you a description here but the site won’t allow us.
WebAug 11, 2014 · The thyroid gland contains two main types of cells: follicular cells that produce thyroxin and C cells that produce calcitonin. A thin fibrous capsule with blood vessels, lymphatics, and nerves, most prominent at …
WebThis study investigated the effects of thyroid disruption of malathion in Fischer rat thyroid follicular cell line, FRTL-5. Transcriptional and translational analyses on thyroglobulin … can jehovah witnesses watch animeWebGlycosylphosphatidylinositol (GPI) acts as an apical targeting signal in MDCK cells and other kidney and intestinal cell lines. In striking contrast with these model polarized cell … five ways to wellbeing fife nhsWebThe Fischer Rat Thyroid Cell Line FRTL-5 cell model, derived from a Fischer rat thyroid and displaying a follicular cell phenotype, was used to investigate a possible causal relationship between intracellular Zn levels and thyroid function. can jehovah witnesses listen to musicWebRat thyroid 細胞株の説明 This thyroid cell line has been established from normal thyroid glands from 5 to 6-week-old Fischer rats. FRTL-5 is a clonal line of the continuously cultured FRTL cells derived by successive clonal isolation. can jehovah witnesses get divorcedWebSecond-order testing for autoimmune thyroid disease, including: -Differential diagnosis of etiology of thyrotoxicosis in patients with ambiguous ... Comparison of thyrotropin-receptor antibodies measured by four commercially available methods with a bioassay that uses Fisher-rat thyroid cells. Clin Chem. 2003 Aug;49(8):1402-1404; package insert ... can jehovah witnesses watch tvWebIn contrast to many other thyroid-restricted genes, SLC26A4 messenger RNA (mRNA) levels are not regulated by TSH in Fisher rat thyroid cell line 5 (FRTL-5) cells (Royaux et al., 2000). It is, however, significantly upregulated by TG, the major component within the luminal space of the follicle, which forms the functional unit of the thyroid. five ways to wellbeing frameworkWebAug 8, 2014 · Distinction between focal, diffuse, and cystic thyroid follicular hyperplasia is recommended and should be included as a qualifier of the diagnosis. The nature of any associated hypertrophy in follicles with … five ways to wellbeing giving