WebJun 21, 2024 · The structural dynamics of the chromo-shadow domain (CSD) and chromodomain (CD) of human HP1 proteins essential for heterochromatin formation … WebDec 3, 2024 · By computational analysis, we found at L1's C-terminal end the chromo shadow domain-binding motif PxVxL, which directs the binding of nuclear proteins to …
Chromo shadow domain - Wikipedia
WebStructures of the Chromo and Chromo Shadow Domains. Function of the Chromo Domain. Genetic, Cytological, and Molecular Properties of the Chromo Domain. Emerging Research Directions and Recent Developments. References. Citing Literature. Modular Protein Domains. Related; Information; Close Figure Viewer. WebNON_CYTOPLASMIC_DOMAIN: Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region; IPR040445: Potassium channel, inwardly rectifying, transmembrane domain; G3DSA:1.10.287.70: ; IPR013518: Potassium channel, inwardly rectifying, Kir, cytoplasmic; TRANSMEMBRANE: Region of a membrane-bound … flying roach vs cockroach
The HP1a disordered C terminus and chromo shadow domain ... - PubMed
WebDec 15, 2024 · Its chromo shadow domain (CSD) homodimerizes, a requirement for binding protein partners that contain a PXVXL motif. How does HP1a select among its many different PXVXL-containing partners? HP1a binds tightly to Heterochromatin Protein 2 (HP2), but weakly to PIWI. WebProteins that possess a chromo domain are well-known for their roles in heterochromatin assembly and maintenance. The Heterochromatin Protein 1 (HP1) family, with a chromo domain and carboxy-terminal chromo shadow domain, targets heterochromatin through interaction with histone H3 methylated on lysine 9 (H3K9me2/3). Webconserved amino-terminal chromo domain and a structurally related carboxy-terminal motif, the chromo shadow domain.3 Both domains of HP1 are required for binding to native chromatin in vivo, but they contribute differentially to binding in euchromatin and heterochromatin.1 The HP1 chromo domain selectively flying rocket craft